You're Not Getting Older.
You're Getting Downstream.
Watch the full replay of Dr. Pedram Shojai's live webinar on the root cause science of gut health — endotoxemia, the gut-brain axis, precision microbiome medicine, and the 6R Protocol that changes everything.
Plus: a limited-time bundle offer that goes away when the timer hits zero.
If You're Here, You Already Know This
The Merry-Go-Round Has to Stop
Dr. Shojai read hundreds of survey responses before this webinar. Here is what he heard — in your own words.
Persistent fatigue and low energy — even after a full night's sleep
Brain fog so thick you can't get through tasks that used to be effortless
Chronic gut issues — bloating, loose bowels, stomach conditions that never fully resolve
Doctors who keep prescribing pills without ever asking why you have the problem in the first place
Anxiety, depression, or insomnia that no one is connecting to what's happening in your gut
The feeling that you've tried everything — and still don't have real answers
"The conventional medical model is caught in a downstream trap. They're chasing symptoms while the root cause continues to rage."
— Dr. Pedram Shojai
Inside the Webinar
The Science They Never Taught You
In 90 minutes, Dr. Shojai covered more clinically actionable gut health science than most people encounter in years of searching.
The Downstream Trap
Why conventional medicine keeps you sick by treating symptoms instead of root causes — and how to break free.
Endotoxemia: The Silent Killer
How LPS from gut bacteria leaks into your bloodstream and drives virtually every chronic disease in modern humans.
The Gut-Brain Axis
The clear, undeniable science linking your gut to anxiety, depression, brain fog, and insomnia — and why no one is treating it.
The Cardiovascular Connection
The newest science showing most heart disease is immunologically triggered — and those triggers live in your gut and gums.
Food Sensitivity Science
IgG and IgA mediated responses, elimination diets, and how the foods you eat every day may be driving autoimmunity.
Precision Microbiome Medicine
Why taking generic acidophilus for everything is silly — and how targeted strains and specific botanicals actually work.
The 6R Protocol
The exact 6-week roadmap used by functional medicine practitioners to remove, replace, reinoculate, repair, rebalance, and retain gut health.
Vetted Science, Not Noise
How to filter the flood of studies — and why the credibility of research matters more than who's talking loudest on Instagram.
"If you don't swim upstream, you're never actually going to get better. You're not going to get healed if you don't go to the root cause and you're playing whack-a-mole with symptoms."
— Dr. Pedram Shojai, Live Webinar
NYT Bestselling Author
8 Books · 12 Documentary Series
Your Host
Dr. Pedram Shojai
Dr. Shojai ran multi-specialty integrative medicine clinics for over a decade, consulted with 1,400+ companies on corporate wellness, and built one of the first functional medicine practices in the country — alongside Jeff Bland, the father of functional medicine.
After producing 12 documentary series seen by millions, he came back to medicine for one reason: the gap between what the science knows and what patients are actually receiving was unconscionable.
Today he oversees a network of doctors in all 50 states, is a keynote speaker at the two largest dental conferences in the country, and is actively publishing research on the oral-systemic connection — the next frontier in medicine.
Choose Your Path Upstream
You watched the webinar. You know gut health is the key. Choose the path that's right for you — all three include a certified health coach consultation.
Path 1: The Test
For the Analyst Who Needs to See the Data.
You trust what you can measure. You want to see the evidence, connect the dots for yourself, and build a plan based on hard data — not just intuition.
What You Get:
- ✓KBMO FIT22 Food Sensitivity Test — at-home blood spot test identifying your immune reactions to the 22 most common food sensitivities, so you know exactly which foods are triggering your inflammation.
- ✓Gut Barrier Permeability Panel — tests for zonulin, occludin, LPS, and candida to definitively determine whether your gut barrier is compromised and toxins are leaking into your bloodstream.
- ✓Private 30-Minute Health Coach Call — once your results are in, a certified coach walks you through exactly what they mean and what to do next.
Special Event Price
Normally $299
One-time payment. Kit ships to your door.
Path 2: The Course
For the Self-Starter Who Wants a Proven Framework.
You're motivated and ready to act. You want a comprehensive, step-by-step system you can trust — built by the world's leading experts in functional gut health.
What You Get:
- ✓The Complete Upstream Course — the full 6-week, 42-lesson 6R Framework with Dr. Pedram Shojai and Dr. Jeff Bland.
- ✓6 Downloadable Workbooks — weekly field guides with checklists, tracking tools, and action plans.
- ✓Exclusive Dr. Jeff Bland Masterclass Modules — direct teaching from the Father of Functional Medicine, integrated throughout the course.
- ✓The Full Interconnected Docu-Series — all 10 episodes plus the complete bonus library of expert Q&As, guides, and masterclasses.
- ✓Lifetime Access — revisit the lessons, re-download the workbooks, and receive all future updates at no extra cost.
Special Event Price
Normally $399
One-time payment. Instant access.
Already have testing? This is your path.
Get the Course →Path 3: The Upstream Bundle
The Complete System: Test, Learn, and Heal.
Everything in Paths 1 and 2 — combined into one complete clinical system. Get your personal data, follow the exact protocol to fix what the data reveals, and have a certified coach guide you every step of the way.
What You Get:
- ✓KBMO FIT22 Food Sensitivity Test — clinical-grade at-home blood spot test identifying your immune reactions to the 22 most common food sensitivities.($199 value)
- ✓Gut Barrier Permeability Panel — tests for zonulin, occludin, LPS, and candida to definitively confirm whether your gut barrier is compromised.($150 value)
- ✓The Complete Upstream Course — the full 6-week, 42-lesson 6R Framework taught by Dr. Pedram Shojai and Dr. Jeff Bland.($299 value)
- ✓Exclusive Dr. Jeff Bland Masterclass Modules — direct teaching from the world's foremost authority on functional gut health.($497 value)
- ✓The Full Interconnected Docu-Series — all 10 episodes plus the Director's Cut, the complete bonus library, and every expert Q&A and masterclass.($497 value)
- ✓6 Downloadable Workbooks — weekly field guides with checklists, tracking tools, and action plans to keep you on protocol.($97 value)
- ✓Private 1-on-1 Health Coach Call — a certified functional medicine health coach walks you through your personal test results and builds your exact action plan.($250 value)
- ✓Lifetime Access + All Future Updates — revisit the protocol, re-download the workbooks, and receive every new lesson and update at no extra cost.
What You'd Pay Separately
Get everything together for just $399 — event pricing only.
Special Event Price
Normally $498
One-time payment. Kit ships to your door + instant digital access.
⚡ Special Event Pricing — This bundle is only available at this price during this event. It will not be offered at $399 again.
Get the Upstream Bundle →🔒 Secure checkout. 30-Day Gut Reset Promise included. · HSA/FSA eligible — email us for the link
The App — Included in Course & Bundle
A $2,000 Tool. Yours for $299.
Dr. Shojai built this app because nothing like it existed. It is the tool he uses with his own doctors and coaches — and it's being offered to you before it becomes a practitioner certification.
AI Gut Tutor
Ask anything. Get answers from the combined knowledge of the top functional medicine experts in the world — not a podcaster with an opinion.
Daily Research Feed
New studies pulled every day and scored for credibility — sample size, replication status, funding transparency, and more. Know what's real.
Lab Data Integration
Upload your test results and get targeted, personalized recommendations based on what's actually happening in your body — not generic protocols.
The Upstream Button
One click connects the dots between your symptoms, root causes, and the upstream triggers driving them. The map of your health, finally visible.
6R Protocol Tracker
Follow the exact 6-week protocol step by step. No confusion about what to do, when to do it, or why it matters.
Precision Supplement Guidance
Targeted strains, specific botanicals, and evidence-based protocols — not the generic acidophilus that everyone sells for everything.
The Information Should Be at Your Fingertips.
Waiting for some person to tell you the answer hasn't really served you. The tools exist. The science is clear. The only question is whether you're going to use them.
This pricing disappears when the timer hits zero. It will not come back.
Common Questions
Dr. Shojai answered these live during the webinar.